The family that eats together stays together: new p53 family transcriptional targets in autophagy.
نویسندگان
چکیده
Autophagy is a biological process that is crucial to maintain cellular homeostasis and is regulated by several metabolic pathways, including the p53 tumor suppressor pathway. In this issue of Genes & Development, Kenzelmann Broz and colleagues (pp. 1016-1031) show how the p53 family as a whole, including p63 and p73, collaborate in controlling autophagy to support tumor suppression.
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ورودعنوان ژورنال:
- Genes & development
دوره 27 9 شماره
صفحات -
تاریخ انتشار 2013